虎杖干预糖尿病肾病作用与研究思路探讨

Intervention of Rhizoma Polygonic Cuspidati on Diabetic Nephropathy

摘要:

虎杖对糖尿病肾病干预作用可能与其清热解毒,利湿,活血化瘀等功效有关。其作用机制可能较为复杂,改善微循环、降低血脂等可能是其重要作用途径。根据虎杖作用特点,选用血瘀、痰湿等糖尿病肾病模型来研究虎杖对糖尿病肾病的干预作用较好。

关键词:虎杖;糖尿病肾病;机制

Abstract:

The intervention of Rhizoma Polygoni Cuspidati on diabetic nephropathy might be relevant to its actions of Qingrejiedu,Lishi and Huoxiehuayu.Its mechanism is complicated,and its actions such as improving hemorheological disorders,lowering serum glucose level etc might be the main approaches relevant to the intervention on diabetic nephropathy.In terms of the acting characteristics of Rhizoma Polygoni Cuspidati,for studying the intervention of Rhizoma Polygoni Cuspidati on diabetic nephropathy it is appropriate to choose mouse models of Xieyu and Tanshi.

Key words:Rhizoma Polygoni Cuspidati;diabetic nephropathy;mechanism