天然澄清剂在银翘解表口服液中的应用

Application of Gas Chromatography for Pesticide Residues Analysis in Chinese Medicine

摘要:

目的: 为更好地对中药进行安全性评价,本文系统综述了气相色谱新技术在中药农药残留检测中的应用及样品前处理方法的研究进展。 方法: 运用归纳对比的方法,系统分析比较了气相色谱样品前处理技术中的固相萃取、凝胶渗透色谱、超临界流体萃取、加速溶剂提取、基质固相扩散、固相微萃取等方法在中药农残检测中的应用;并对气相色谱中常用的电子捕获、硫磷、氮磷及质谱检测器在中药农残检测中的特性及适用范围进行了比对分析。 结果: 气相色谱及其前处理技术是一种成熟、稳定的中药农药残留的检测手段。 结论: 气相色谱及其新技术在中药农残检测中越来越广泛的应用,有利于促进中药农残检测标准与国际接轨,更好的保障中药及其制剂的使用安全。

Abstract:

Objective: In order to evaluate the safety of Chinese medicine comprehensively, the development of pesticide residues determination in Chinese medicine by gas chromatography (GC) was summarized in this paper. Methods : Through analytic comparison, the developments of sample pretreatments were summarized systematically, including solid-phase extraction (SPE), gel permeation chromatography (GPC), supercritical fluid extraction (SFE), accelerated solvent extraction (ACE), matrix solid phase dispersion (MSPD), solid-phase micro-extration (SPME) and headspace analysis (HS). In addition, the comparison of gas chromatography detectors such as mass spectrometry (MS), electron-capture detector (ECD), flame photometric detector (FPD) and nitrogen–phosphorus detector (NPD) were also discussed. Results: Gas chromatography is a mature technology to accomplish pesticide residues determination in Chinese medicine. Conclusion: Gas chromatography and relevant new techniques are wildly used in safety evaluation of Chinese medicine and its preparations, which will be benefit for the international development and import of Chinese medicine.