消癥汤对子宫内膜异位症模型大鼠腹腔液PGF2α和 血清CA125水平的影响

Influence and of Endometriosis Model Mouse’s Liquid of Abdominal Cavity PGF2a and Serum CA125which Treated with Xiaozheng Decoction(XZD)

摘要:

目的 :探讨消癥汤对子宫内膜异位症模型大鼠腹腔液PGF_2α和血清CA₁₂₅的影响。 方法 :实验分为生理盐水组,西药对照组,中药高剂量组,中药低剂量组,每组10只,采用ELISA法,观察子宫内膜异位症模型大鼠腹腔液PGF_2α及血清CA₁₂₅水平浓度。 结果 :消癥汤能够降低子宫内膜异位症模型鼠血清CA₁₂₅水平、腹腔液中PGF_2α含量,对异位子宫内膜具有一定的抑制作用。 结论 :消癥汤能降低血清CA₁₂₅水平、腹腔液中PGF_2α含量,抑制异位子宫内膜的异常增生。

Abstract:

Objective: To observe the effect of Xiaozheng decoction(XZD) resolve in treating_endometriosis model mouse and to explore its Liquid of abdominal cavity PGF_2a、serum CA₁₂₅. Method: Divide into four groups, the group treated with physiological saline, the group treated with western medicine, the group treated with traditional Chinese medicine of high dosage, and the group treated with traditional Chinese medicine of low dosage, each group with ten mouses. By ELISA to observeendometriosis model mouse’s serum CA₁₂₅and_liquid of abdominal cavity PGF_2a. Result: XiaoZheng Decoction(XZD) reduce the serum CA₁₂₅,liquid of abdominal cavity PGF_2a of endometriosis model mouse and has some restrained function for endometriosis. Conclusion: XZD has an effect may be achieved by reducing the serum CA₁₂₅,liquid of abdominal cavity PGF_2a,restraining unusual proliferation of endometriosis.