Objective: To observe the effects of beisheng granules on nutritional status in hemodialysis patients with chronic renal failure. Method: The 60 patients were divided into beisheng granules group( n =30) and control group( n =30).AMC, Fr and BMI were measured and the serum level of albumin, pre- albumin and transferrin were tested before and after treatment. The score of Subjective global assessment of nutrition were also computed. Result: In treatment group, the level of albumin, pre- albumin ,transferrin and the score of SGA were increased significantly compared with before treated and the control group. There was no difference of AMC,Fr and BMI between two groups. Conclusion: Beisheng granules can improve nutritional status in hemodialysis patients with chronic renal failure.