Objective: To evaluate the integrated traditional Chinese and western medicine treating ROU effectiveness. Method: 180 patients of ROU were divided into two groups randouly.Each group had 20 patients.The experimental group were treated by integrated traditional Chinese and western medicine..The comparison group were treated by western medicine. Result: The effective rates of experimental group in one year is 97.78%, the effective rates of comparison group in one year is 87.78%. Statistically significant differences were found between two groups.(P<0.05). The effective rates of experimental group after one year is 82.22%, the effective rates of comparison group in one year is 61.11%.Statistically significant differences were found between two groups.(P<0.05). Conclusion: There are excellent effectiveness of integrated traditional Chinese and western medicine treating ROU.