452例临床药物不良反应回顾性分析

Analysis of Adverse Reactions in 452 Cases

摘要:

目的: 分析临床药物不良反应(ADR)的各种情况以指导临床用药。 方法: 回顾性分析临床药物不良反应的情况。 结果: 452例不良反应中青年人明显高于老年人;抗生素类药物居多;较多累及皮肤黏膜系统;大多数为轻度。 结论: 药物不良反应在临床仍普遍存在,应重视药物的合理应用,以避免或减少ADR的发生。

Abstract:

Objective: To investigate drug-induced adverse reactions by analyzing clinical manifestations. Method: Using retrospective methods the clinical drug adverse reactions were analyzed. Result :Based on data of 452 cases,we learnt obviously that the incidence rate in the old is higher than that in the young.The antibiotic drugs account for most adverse reactions,and adverse reactions occur in several systems. The adverse reactions in skin is the highest, while most are slight. Conclusion: Adverse reactions still exist at large in clinic, In order to avoid or reduce the incidence of the reactions, drugs should be used reasonably with caution in patients.