Abstract:The flavonoid compounds have very powerful antioxidant and remove the active ability, can prevent free radicals attackmg DNA and inducing cancer. In cardiovascular system, endocrine system, immune system and antitumor aspects significant pharmacological activities which very ectensive prospect on the duelopment and application the feavondas have. This paper mainly describes the recent natural flavonoids of the extraction process of research, compare to its at the same time. It is concluded that the ultrasonic method with microwave-assisted extraction is simple operation in with short time, can consider to appliy in industrial production scale.