Objective: To optimize the water extraction conditions for solid-fermented Angelica sinensis. Method: Orthogonal design was used in optimizing the extraction conditions while ferulic acid and extract dry weight were adopted as markers. Result: Optimum extraction technology was as follows: the medicinal materials were soaked in water for 0.75 hour, and extracted 2 times with one hour for each time by 12-fold and 8-fold volume of water. Conclusion: Extraction technology established in this experiment is stable and feasible and can be used to extract solid-fermented Angelica sinensis.