正交试验优选心衰宁合剂水提工艺

Study on Optimizing Technological Condition of Water Extraction for Xinshuaining Mixtures by Orthogonal Design

摘要:

目的: 优选心衰宁合剂的最佳水提工艺。 方法: 以人参皂苷Rg₁、人参皂苷Re、人参皂苷Rb₁含量和浸膏得率为考察指标,采用正交试验优选出最佳水提工艺。 结果: 心衰宁合剂最佳水提工艺为第1次加12加倍量水,第2,3次分别加10倍量水,共煎煮3次,每次1h。 结论: 该水提取工艺设计合理,人参皂苷提取率高,稳定可行,方法可重复操作,可为心衰宁合剂的研制提供理论和试验基础。

Abstract:

Objective: To optimize the water extraction process of Xinshuaining Mixtures. Method: Orthogonal design was used to select the water extraction process of Xinshuaining Mixtures with the content of ginsenoside Rg1, ginsenoside Re, ginsenoside Rb1 and the yield of extract as the investigating index. Result: The best water extraction process of Xinshuaining Mixtures was: the first time adding 12 folds water, adding 10 folds water for second and third times, decocting 1 h for 3 times. Conclusion: The established technology was reasonable, feasible and reproducible. It can be used for the development of Xinshuaining Mixtures to provide theoretical and experimental basis.