基于关联规则和复杂系统熵聚类的颜正华诊疗失眠用药规律研究

Analysis of Apriori and Clustering Algorithm on Traditional Chinese Medicine Master YAN Zheng-hua's Medication Rule in Prescriptions for Insomnia

摘要:

目的: 基于中医传承辅助系统软件,分析颜正华教授治疗失眠的用药经验。 方法: 收集颜正华教授治疗失眠的病案,采用关联规则apriori算法、复杂系统熵聚类等无监督数据挖掘方法,确定处方中各种药物的使用频次及药物之间的关联规则,分析颜正华教授治疗失眠的用药经验。 结果: 对筛选出的170处方进行分析,确定处方中药物的使用频次,药物之间的关联规则,挖掘出44个核心组合和7首新处方。 结论: 颜正华教授治疗失眠经验丰富,多将养心安神和重镇安神之品配合使用。中医传承辅助系统对于挖掘名老中医临床经验具有重要实用价值。

Abstract:

Objective:To analyze the composing experience of professor YAN Zheng-hua for treating insomnia by traditional Chinese medicine(TCM)inheritance support system. Method: The prescriptions for insomnia by YAN Zheng-hua were collected,then the data were entered into TCM inheritance support system and analyzed the composing principles by using datamining methods such as revised mutual information,complex system entropy cluster and unsupervised hierarchical cluster. Result: Based on the analysis of 170 prescriptions, the frequency of each herb and association rules among the herbs were computed, 44 core combinations and 7 new prescriptions were mined from the database. Conclusion: Professor YAN Zheng-hua is good at nourishing the heart to calm the mind and tranquillizatting with heavy to relieve insomnia,TCM inheritance support system can be used to analyze clinical experiences of senior TCM doctors.