Abstract:Objective:To compare the changes of chlorogenic acid and luteolin content in sulfur fumigation and drying Lonicera japonica, in order to study the chemical components of L. japonica. Method: The content of chlorogenic acid and luteolin from different origin and different processing methods was determined with HPLC. Result: Chlorogenic acid was significantly increased, while the content of luteolin changed very little after sulfur smoked. Conclusion: The content of chlorogenic acid has increased significantly after sulfur smoked, but the content of luteolin almost had no effect. The content of two components from different areas was changed very widely.