Abstract:Objective: To explore influence factors of female hyperplasia of mammary glands in Zhengzhou city. Method: In 2010 September-2011 May, one group of 435 outpatients with hyperplasia of the mammary glands in the second group of 242 women without hyperplasia of the mammary glands were collected.Using a case-control study method,with the information of the two groups which general, fertility, sociology etc. collection and statistics, to explore the influence factors of patients with hyperplasia of mammary glands by logistic regression analysis. Result: By multivariate logistic regression analysis, the risk factors are that dysmenorrhea, pregnancy times greater than 2 times, stream of people time is more than 2 times, moderate to low family income, interpersonal relations in general, profession mainly doing mental work,work to suppress with higher levels of anxiety and passive smoking;and the protective factors are that lean body mass, higher education, old age at menarche,birth order is more than 2 times,light diet and the occasional drink. Conclusion: The influencing factors of hyperplasia of mammary glands include menstrual and reproductive history, and occupation factors and emotional factors make a great impact on the disease.