中西医结合治疗胸部创伤后急性呼吸窘迫综合征

Combined Treatment of Traditional Chinese Medicine and Western Medicine for Acute Respiratory Distress Syndrome after Chest Trauma

摘要:

目的: 探讨中西医结合治疗胸部创伤后急性呼吸窘迫综合征的临床疗效。 方法: 选取我院收治的胸部创伤后急性呼吸窘迫综合征患者80例,随机分为对照组(常规西医治疗)和治疗组(在对照组治疗基础上加服凉膈散加减,1剂/d,疗程 10 d)。观察比较两组患者住院时间、机械通气时间、氧合指数、动脉血氧分压的变化,以及并发症、死亡率。 结果: 治疗组在治疗后48,72 h动脉血氧分压、治疗后24,36,48,72 h氧合指数较对照组有明显改善(P<0.05),治疗组比对照组在机械通气时间[(7.31±3.12)d vs(10.22±4.42)d]、平均住院天数[(12.32±2.35)d vs (16.43±3.43)d]及死亡率(22.5% vs 42.5%)均有明显降低(P<0.05)。 结论: 采用中西医结合治疗胸部创伤后急性呼吸窘迫综合征可明显地缩短机械通气时间;缩短住院天数;提高抢救成功率,降低死亡率。

Abstract:

Objective: To observe the clinical efficacy of combination of traditional Chinese medicine and western medicine for treating acute respiratory distress syndrome (ARDS) after chest trauma. Method: Eighty patients with ARDS treated in our hospital divided into 2 groups randomly, the control group (routine western medicine therapy) and the treatment group (modified Liangge San one dose daily, 10 d for a course, based on the routine western medicine). Hospitalization duration, mechanical ventilation time, oxygenation index, the change of arterial partial pressure of oxygen, complications and death rate in the 2 groups were observed and compared. Result: Arterial partial pressure of oxygen at 48, 72 h and oxygenation index at 24.36, 48, 72 h after treatment in the treatment group improved more evidently than those in the control group (P<0.05). Comparisons on mechanical ventilation time [(7.31±3.12)d vs (10.22±4.42)d], average hospitalization days [(12.32±2.35)d vs (16.43±3.43)d] and death rate (22.5% vs 42.5%) between treatment group and control group showed significant differences(P<0.05). Conclusion: Combined treatment of traditional Chinese medicine and western medicine for treat ARDS after chest trauma can not only reduce evidently mechanical ventilation time and hospitalization duration, but also improve success rate of rescue and reduce mortality.