基于关联规则和复杂系统熵聚类的颜正华教授治疗血瘀证用药规律研究

Analysis on Traditional Chinese Medicine Master YAN Zheng-hua’s Medication Rule in Prescriptions for Syndrome of Blood Stasis Based on Apriori and Clustering Algorithm

摘要:

目的：基于中医传承辅助系统软件，分析国医大师颜正华教授治疗血瘀证的用药规律。方法：收集颜正华教授治疗血瘀证的病案，采用关联规则apriori算法、复杂系统熵聚类等方法，确定处方中各种药物的适用频次及药物之间的关联规则，分析颜正华教授治疗血瘀证的用药经验。结果：对筛选出的114个处方进行分析，确定处方中药物的使用频次，药物之间的关联规则，挖掘出12个核心组合和6个新处方。结论：颜正华教授治疗血瘀证经验丰富，多用活血化瘀、调经止痛之品。中医传承辅助系统对挖掘名老中医临床经验具有重要的实用价值。

Abstract:

Objective: To analyze the composing experience of professor YAN Zheng-hua for syndrome of blood stasis by using traditional Chinese medicine(TCM)inheritance support system. Method: Cellecting the prescriptions for syndrome of blood stasis,then enter the data into TCM inheritance support system and analyze composing principles by using datamining methods such as revised mutual information,complex system entropy cluster and unsupervised hierarchical cluster. Result: Based on the analysis of 114 prescriptions, the frequency of each herb and association rules among the herbs are computed, 12 core combinations and 6 new prescriptions are mined from the database. Conclusion: Professor YAN Zheng-hua is good at activating blood circulation to dissipate blood stasis and regulating qi to relieve ache,TCM inheritance support system can be used to analyze old TCM doctor' clinical experience.