益糖康干预糖调节受损的代谢综合征疗效评价

Evaluation Study of Yitangkang in Treating Patients with Metabolic Syndrome and Impaired Glucose Regulation

摘要:

目的: 本研究通过随机、双盲、平行对照、多中心临床试验的方法,进行益糖康干预代谢综合征的有效性及临床方案的优效性的前瞻性研究.方法: 收集符合中医辨证诊断标准的代谢综合征患者165名,随机分配到治疗组和对照组中.对西医效应指标(血糖、糖化血红蛋白、体重指数)和中医效应指标(中医证型指标、中医证候指标、生存质量积分等)进行治疗前后及组间的比较.结果: ①益糖康可以改善患者空腹血糖、餐后2 h血糖、血压和体重指数.②益糖康可提高空腹血糖、餐后2 h血糖和体重指数的达标率.③益糖康能够有效地改善代谢综合征患者的主要临床症状及全身状况,提高患者的生存质量.结论: ①益糖康具有降低血糖、体重以减少代谢综合征危险因素的临床作用.②中医药治疗方案可延缓代谢综合征病情发展,提高患者的生存质量,值得推广应用.

Abstract:

Objective:A randomized, double-blind, parallel-group, multi-center prospective clinical trial was conducted to the superiority and efficacy study of Yitangkang in treating patients with metabolic syndrome. Method: One hundred and sixty-five patients with metabolic syndrome were randomly divided into the observation group and the control group. The western medicinal targets (glucose, glycosylated hemoglobin, body mass index), and traditional Chinese medicinal (TCM) indicators (TCM patterns indicators, TCM syndrome indicators, quality of life score, etc.) were compared between groups before and after treatment. Result: ①Yitangkang can improve fasting glucose, 2-hour postprandial blood glucose, blood pressure and body mass index of patients. ②Yitangkang can increase the compliance rate of fasting glucose, 2-hour postprandial glucose and body mass index. ③Yitangkang can effectively improve the clinical symptoms and systemic conditions, and improve the quality of life in patients with metabolic syndrome. Conclusion: ①Yitangkang can reduce the clinical risk factors by decreasing the blood glucose and weight of patients with metabolic syndrome. ② Chinese medicine treatment can delay the progression of the metabolic syndrome and improve the quality of life of patients, which are worthy widely applied.