纳秒脉冲电场对中成药灭菌效果的初步考察

Preliminary Research on Sterilization Effect of Chinese Patent Medicine by Nanosecond Pulsed Electric Fields

摘要:

目的: 考察纳秒脉冲电场对不同剂型中成药的灭菌效果. 方法: 选择大山楂丸、舒心糖浆、益母草膏3种典型的中成药为研究对象,场强选择40,50,60 kV·cm^-1,脉冲数10,100次,通过2个参数交互作用,采用纳秒脉冲电场发生器对中成药进行电击处理,利用平皿法检查灭菌效果. 结果: 在选定的参数条件下,该法对大山楂丸细菌的灭菌无效,对舒心糖浆和益母草膏灭菌合格. 结论: 纳秒脉冲电场对液体和半固态中成药制剂灭菌效果较好.

Abstract:

Objective: To investigate sterilization effect on Chinese patent medicine by nanosecond pulsed electric fields. Method: Taking Dashanzha pills,Shuxin syrup and Yimucao pastes as research objects,field strength was 40,50,60 kV· cm^-1 and pulse frequency was 10,100 times,by interaction of these two parameters,Chinese patent medicine was electric shocked by nanosecond pulsed electric fields generator,sterilization effect was detected by plating method. Result: Sterilization by nanosecond pulsed electric fields was effective to Shuxin syrup and Yimucao pastes while invalid to Dashanzha pills. Conclusion: Sterilization is effective to liquid and semi-solid Chinese patent medicine by nanosecond pulsed electric fields.