Objective: To study the chemical constituents of the seeds of Nandina domestica. Method: The compounds were isolated with column chromatography and their structures were elucidated by means of spectral analysis. Result: Nine phenolic compounds were isolated and their structures were identified as syringic acid(1), ethyl gallate(2), ellagic acid(3), caffeic acid(4), p-hydroxybenzoic acid(5), gallic acid(6), protocatechuic acid(7), 3,3'-di-O-methylellagic-4-O-β-D-glucoside(8), bergenin(9), respectively. Conclusion: The compounds 1-9 were first isolated in Nandina domestica.